Life & Death is an almost serious attempt at simulating the life (and works) of your average surgeon and can thus be rather demanding and confusing at the beginning. Things do, of course, soon start making sense and get way more interesting as you progress, though the sadistic joke of operating without anesthesia never gets old.
Anyway. If you own an Atari ST, you can now grab a lavishly boxed copy of Life & Death via eBay. It comes complete with manual, gloves, mask and everything, but above all with the hilariously written and historically accurate The History of Surgery. Seller ships to the Americas, Europe, Asia and Australia.